Company BUSINESS

- ABOUT US
- BUSINESS
- R&D

홈
BUSINESS
PHARMACEUTICALS

ODF BUSINESS

ctcbio’s Unparalleled Expertise,
Convenient and Effective ODF Technology

What is ODF(Orodispersible Film)?

ODF refers to an oral dissolving film that melts naturally in the mouth. It is easy to administer and absorbs well. It is a thin film-type formulation that dissolves by saliva in the mouth even without water, so it is easy to consume, and the active ingredient is absorbed directly through the mouth or mucous membrane.

This fast-acting dissolving type of formulation was developed in the late 1970s, starting with ODT (Orodispersible Tablets) as an alternative for children and elderly patients who had difficulty swallowing oral solid formulations such as tablets and capsules.

ODF has several advantages, such as convenient administration where water is not required, and improved patient drug compliance. In addition ODF can be used for prompt treatment with first aid drugs in emergency situations due to its instant efficacy, and it also provides for more accurate administration compared to liquid drugs.

ctcbio’s ODF Business

Pharmaceuticals

R&D of the formulation of generic products to improve the convenience of taking existing products (tablets, capsule, etc.)

R&D to improve bioavailability by changing the administration of existing drugs

Research of the application of ODF formulations to new drugs
Neutraceuticals

Development of neutraceuticals to improve the convenience of taking daily supplements
Animal Health

Development of animal drugs and feed ingredients to improve ease of administration
OEM/ODM Business

ODM and OEM business, domestically and internationally, with ctcbio’s ODF product development and manufacturing know-how

Definition of ODF

ODF is a formulation of thin film that disintegrates or dissolves in the mouth without water. It is easy to administer and the active ingredient can be absorbed through the mouth or mucous membrane.

This fast-acting dissolving type of formulation was developed in the late 1970s, starting with ODT (Orodispersible Tablets) as an alternative for children and elderly patients who had difficulty swallowing solid oral formulations (tablets, capsules), followed by the development of ODF.

Convenient administration
(no water needed)
Improvement of the patient's drug compliance due to convenient administration
Improving patients' awareness of drugs with negative indications
Increase bioavailability and realize rapid drug expression through the use of mucosal administration in the mouth
In emergency situations, prompt treatment with first aid drugs possible
Accurate dosage compared to liquid drugs

Product List

Pharmaceuticals Prescription based
Pharmaceuticals OTC
Neutraceuticals
Animal Health
Animal Health_Feed

Product Name	Strength	Indication	Korea·Export	Vendor·authorized company	Stage	Remarks
Post development Sildenafil (Please)	100mg, 50mg	Erectile Dysfunction	Korea	ctcbio + 4	For sale	Dongkook Pharmaceutical, Jeil Pharmaceutical Company, Huons, Alvogen
Post development Sildenafil (Please)	100mg, 50mg	Erectile Dysfunction	Export	14 countries	For sale	Renewing permits in some countries
Post development Tadalafil (Goden)	20mg, 10mg, 5mg	Erectile Dysfunction	Korea	Menarini Korea	For sale	-
Post development Tadalafil (Goden)	20mg, 10mg, 5mg	Erectile Dysfunction	Export	25 countries	For sale	Renewing permits in some countries
Post development Desmopressin Acetate(Duressin)	0.2mg, 0.1mg	Nycturia	Korea	JW Pharmaceutical	For sale	No product on sale under ctcbio’s name
Post development Entecavir(Pilcrude)	1.0mg, 0.5mg	Chronic hepatitis B	Korea	ctcbio	Not for sale	-
Post development Entecavir(Pilcrude)	1.0mg, 0.5mg	Chronic hepatitis B	Export	Abbott	Not for sale	Distribution rights belong to Abbott
Post development Donepezil(Remecept)	9.12mg, 4.56mg	Alzheimers-type dementia	Korea	ctcbio	Not for sale	-
Post development Sildenafil citrate	100mg, 50mg	Erectile dysfunction	Korea	ctcbio	Applying for permit	-
Post development Varenicline salicylate	1.0mg, 0.5mg	Antismoking therapy	Korea	ctcbio	Not for sale	-
Development discontinued Badenafil hydrochloride (erectile dysfunction), Ondansetron (nausea), Zolmitriptan (migraine), Memantin hydrochloride (dementia), etc
Research stage Orlistat(Undecided)	120mg, 60mg	Obesity	-	-	Research stage	-
Research stage Miscellaneous	-	-	-	-	Product development stage	2-3 types

Product Name	Strength	Indication	Korea·Export	Vendor·authorized company	Stage	Remarks
Post development Medizine Hydrochloride Hydrate(Meclin)	25mg	Motion sickness	Korea	Korean Drug	For sale	Not for sale under ctcbio’s name
Post development Dexchlorpheniramine maleate + 2(Nose Quick)	2.0mg, 5.0mg, 0.2mg	Cold	Korea	ctcbio	Not for sale	Product filing completed
Post development Simethicone	62.5mg	Removal of gas from the stomach	Korea	ctcbio	Not for sale	Product filing completed
Post development Loratadine (Allerno)	10mg	Antihistamine	Korea	ctcbio	Not for sale	Product filing completed

Product Name	Strength	Stage	Remarks
Development phase Glutathione	100mg	Study completed	Request by neutraceutical division
Development phase Probiotics	100mg	Stability testing	Testing stability; neutraceutical division
Development phase Gingko Biloba Extract	50mg	Study completed	Adjusting taste and scent

Active Ingredient	Strength	Indication	Species	Stage	Remarks
Ivermectin/Pyrantel	68mcg/163mg	Heartworm disease	Dog	On hold (Prescription study completed)	No stability-testing performed
Ivermectin	68mcg	Deworming	Dog
Sildenafil citrate	140.45mg/kg	Heart failure	Dog
Tolfenamic acid	20mg/kg	Pain relief after surgery	Dog, Cat
Enalapril maleate	10mg	Congestive heart failure	Dog
Ursodeoxycholic acid	100mg/kg	Improvement of liver function	Cat

Type	Species	Stage	Remarks
Nutritional supplement for joints	Cat, dog	On hold (Prescription study completed)	No stability-testing performed
Nutritional supplement for heart disease
Nutritional supplement for liver
Nutritional supplement for eye health
Nutritional supplement for skin
Nutritional supplement for cognitive function
Sedative supplement